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Dr.Hesham Gomaa is a Specialist pediatrcian who has serviced the DHA over 25 years. We provide excellent care to patients from birth to 19 years of age. Our primary focus is to give your child the best diagnosis possible, while sharing vital health-related information with you to further improve your child's health. We care about every child's well-being, which is why we take the time to get to know each of our patients very well.
Just edit this element to add your own HTML.What is G6PD deficiency? Glucose-6-phosphate dehydrogenase (G6PD) is an enzyme that helps red blood cells to work properly. Some people have less than the usual amount of G6PD in their red blood cells. This is called G6PD deficiency, or favism. Most people with G6PD deficiency have completely normal health, but sometimes it can cause problems. This guide explains the problems G6PD deficiency may cause and what to do if your child has problems. G6PD deficiency is passed on from parents to children G6PD deficiency is an inherited disorder, which means it is passed from one or both parents to the child. It affects males more often than females. About 400 million people worldwide have G6PD deficiency. Anyone can have G6PD deficiency, but it is most common in people whose families came from Africa or other areas where malaria has been common, such as the Mediterranean, Caribbean, and South-East Asia. G6PD deficiency is usually milder in people of African origin and more severe in people of Mediterranean and Asian origin. G6PD protects red blood cells Red blood cells carry oxygen to all parts of the body. G6PD is an enzyme that helps the red blood cells to function normally. It also helps protect them against substances that can build up when you have a fever or take certain medicines. If a person does not have enough G6PD, some of their red blood cells may be destroyed when they have a fever or when they take certain medicines. The breakdown of red blood cells is called haemolysis (say: he-MOLL-iss-iss). If this happens, the person may not have enough red blood cells and may become anaemic. More about G6PD Deficiency ‘triggers’ Infections like Salmonella and E.coli can act as triggers for G6PD deficient individuals (source: aafp.org – Diagnosis and Management of G6PD Deficiency), so it is important to prepare your homemade baby food with scrupulous care, to avoid the growth of bacteria. This includes the correct cooking, storage, and reheating of baby’s meals. Please visit our page: How to Safely Prepare Baby Food for more information. By the same token, preparing your own baby food gives you the confidence to know that your little one’s food has been hygienically and safely prepared – another reason that we feel homemade baby food is absolutely ideal for babies with G6PD Deficiency! In addition to infections, certain medications can act as triggers – you’ll find a very detailed list here. So, too, can chemicals used in food preservation, such as sulfites (also spelled sulphites in some parts of the world) and artificial food colourings (we suggest some safe, natural food colourings here). Sulfites are often found in: baked items, like cakes and cookiesbottled lemon and lime juicefrozen or canned fruits and veggiescornmeal and cornstarchcrackerssauces like ketchup and mustardprocessed meat, like hot dogs and sausagesdried fruits and veggies (including raisins)dried spices and herbsteafish and shellfishfresh grapesjams, preserves and fruit pie fillingslettucefruit and veggie juicesprepared potatoes (like frozen fries, dehydrated potato)chips and candyprepared rice and noodle mixessoy productsprocessed tomato (like tomato puree or tomato paste)vinegar Your child should not take certain medicines If your child has G6PD deficiency, he should not take any of the following medicines: acetylsalicylic acidâ€‹ (ASA or Aspirinâ€‹) ascorbic acid (Vitamin C) chloramphenicol chloroquine dapsone dimercaprol doxorubicin mepacrine methylene blue methyldopa nalidixic acid naphthalene nitrofurantoin phenazopyridine primaquine quinine sulfacetamide sulfadiazine sulfamethoxazole (Co-trimoxazole, Septra) sulfanilamide sulfapyridine sulfisoxazole (Pediazole) toluidine blue Problems for children and adults Most people with G6PD deficiency have completely normal health, but sometimes it can cause problems. Some children and adults with G6PD deficiency may develop haemolysis and anaemia after they are exposed to any of these triggers: if they get a fever if they take certain medicines listed later in this guide if they eat fava beans; this is called favism If your child is exposed to a trigger that causes haemolysis, sometimes there are no symptoms at all. In more serious cases, your child may have one or more of the following symptoms of anaemia: pale skin fatigue rapid heartbeat rapid breathing shortness of breath jaundice (yellowing of the skin and eyes) backache dark, tea-coloured urine
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Camel milk as a potential therapy in autism spectrum disorder (ASD)
Autism spectrum disorder (ASD) is a severe neurodevelopment disorder with onset prior to 3 years of age . It is characterized by impairments in social orientation, communication, and repetitive behaviors . In addition to behavioural impairment, ASD is associated with high prevalence of autoimmune disease , gastrointestinal disease and dysbiosis , and mental retardation .
The prevalence of autism has increased over the last several decades. The incidence of ASD in United States increased in 2008 to 1 in 88 children . Prevalence of autism spectrum disorders in Saudi Arabia is estimated to be 6 : 1000 . Increased prevalence has great effects on public health implications and has stimulated intense research into potential etiologic factors.
Extensive studies have demonstrated that oxidative stress plays a vital role in the pathology of several neurological diseases such as Alzheimer's disease , Down syndrome , Parkinson's disease , schizophrenia , bipolar disorder , and autism .
Oxidative stress occurs when reactive oxygen species (ROS) levels exceed the antioxidant capacity of a cell. It acts as a mediator in brain injury, strokes, and neurodegenerative diseases ; thus, the control of ROS production is necessary for physiologic cell function. The ROS within the cells are neutralized by antioxidant defence mechanisms, including superoxide dismutase (SOD), catalase, and glutathione peroxidise (GSH-Px) enzymes. The increased production of ROS both centrally (in the brain) and peripherally (in the plasma) may result in the reduction of brain cell number leading to autism pathology and apoptosis .
Several studies have suggested the contribution of oxidative stress to the development of autism. These studies demonstrated the alteration of antioxidant enzymes like GSH-Px, MPO, and SOD, lipid peroxidation, antioxidant proteins as ceruloplasmin and transferrin, and detoxifying metabolites like GSH, as well as antioxidant nutrient vitamins and minerals .
Camel milk has emerged to have potential therapeutic effects in many diseases such as food allergy, diabetes mellitus [27, 28], hepatitis B , autism , and other autoimmune diseases . It has a unique composition that differs from other ruminants' milk. It contains lower fat, cholesterol, and lactose than cow milk, higher minerals (calcium, iron, magnesium, copper, zinc, and potassium) and vitamins A, B2, E, and C compared to cow milk [32, 33], and it contains no beta lactoglobulin and beta casein which are the main causative of allergy in cow's milk . Furthermore, camel milk contains various protective proteins, mainly enzymes which exert antibacterial, antiviral, and immunological properties [35, 36]; these include immunoglobulins, lysozymes, lactoferrin, lactoperoxidase, N-acetyl-§-glucosaminidase (NAGase), and peptidoglycan recognition protein (PGRP) , which are crucial in preventing food allergy and rehabilitating the immune system . Camel milk proved its potential effect in the treatment of food allergies, due to its inflammation-inhibiting proteins, and hypoallergenic properties, in addition to its smaller size nanobodies, which are different than those found in human. Camel milk nanobodies, as a single domain, show many promising and therapeutic potencies in infection and immunity
In study aimed to investigate the role of the effectiveness of camel milk (CM) (raw and boiled) on thymus and activation-regulated chemokine (TARC) serum levels and childhood autism rating scale (CARS) score in subjects with autism and compared to placebo group (cow milk);the study reveals CM administered for 2 wk significantly improved clinical measurements of autism severity and decreased serum level of TARC in autistic children.
(Pediatr Res. 2014 Apr;75(4):559-63. doi: 10.1038/pr.2013.248. Epub 2013 Dec 27.)
In one Patient report Published in Glob Adv Health Med. 2013 Nov;2(6):78-80. doi: 10.7453/gahmj.2013.094.
This patient report is about my son, who was diagnosed with autism spectrum disorder (ASD) at 3 years of age, and the effects I observed when he began drinking camel milk daily. Beginning at age 9, he drank one half cup of raw camel milk a day and experienced overnight an improvement in his symptoms. His continued regular consumption of camel milk was associated with sustained symptom improvements for 6 consecutive years (2007-2013).